Postdoctoral Position in Tumour Model Design and Chiral Plasmonics
Published: 10/10/2024
Deadline extended
Deadline: 02/12/2024
Envisaged Job Starting Date: January 1st, 2025
A postdoctoral position is available in the BioNanoPlasmonics Laboratory, led by Prof. Luis Liz-Marzán. The successful candidate will develop and optimize advanced organoid-based breast cancer models for applications in which non-invasive chiroptical-based nanoparticle sensing will be conducted.

The position is directly linked to the project BIOSCAFFONC “3D printed BIOsensing cellular SCAFFolds for precision ONCology”, selected for funding by the Spanish Research Agency (AEI). BIOSCAFFONC aims to develop 3D printed scaffolds suitable for the development of breast cancer in vitro models with in situ sensing capabilities. The project will simultaneously follow two lines of investigation, namely the development of biocompatible materials to mimic the tumour microenvironment (TME), and of chiroptic gold nanoparticles (NPs) as substrates for sensing of biomolecules or physical changes related to the TME. The ultimate goal is the development of non-invasive biosensing techniques via in situ spectroscopic means, combining knowledge from the fields of biomaterial design, in vitro organoid models, advanced plasmonic NP synthesis methods, and chiroptical related spectroscopy, amongst others.

We are looking for a qualtified researcher with desire to work at the interface of biology, chemisty, and physics, combining novel biosensing techniques with advanced cell models. The research will be interdisciplinary, and the candidate should expect to work in a multidisciplinary and collaborative environment.

The main tasks of the position are:

  • Design and synthesis of biocompatible materials, suitable for 3D printing and scaffold fabrication.
  • Cell culture of organoids, including authentication of cell phenotype.
  • Design of optimal cancer cell and tumor microenvironment, including cell media optimization in heterogeneous cell cultures.

Key responsibilities include conducting independent and collaborative research, data processing and analysis, and preparation of presentations, scientific manuscripts, and internal reports. Proactive communication with peers and supervisors is essential.

The project is to be carried out at CIC biomaGUNE, a vibrant multidisciplinary and international research institute in San Sebastian, Spain. CIC biomaGUNE has established a state-of-the-art research program at the interface between the chemical, biological and physical sciences. It offers excellent working conditions and is well equipped with instrumentation and facilities.

Required Education Level:

A PhD in a relevant area of Biotechnology, Biomaterials Science, Biology, Biochemistry, Bionanotechnology, or related areas.

Experience in the fields of biomaterial design, polymer synthesis, rheology, 3D bioprinting, advanced 3D cell culture, organoid culture, fluorescence confocal microscopy, proteomics. and/or SERS is highly desirable. Prior experience in the development of in vitro cancer models will be considered an advantage.

Required Skills/Qualifications:

Candidates must have a Doctoral degree at the time of hiring. The candidate is expected to have an interest in multidisciplinary work, and the capacity to work in an international environment. Excellent interpersonal skills as well as written and oral communication skills in English are required.

Duration:

The successful candidate will be hired by CIC biomaGUNE with a full-time temporary contract in the framework of assigned functions in the project development.

Project Funding:
BIOSCAFFONC - PID2023-151281OB-I00 - (Spanish Research Agency - AEI)
Informal Inquiries:

Informal requests for additional information can be sent to Luis Liz-Marzan at llizmarzan@cicbiomagune.es

Applications sent directly to the emails listed above will be NOT be accepted.

Equal opportunities Policy:

CIC biomaGUNE is proud to be an equal opportunity employer and applicants will receive consideration for employment without regard to: age, color, disability, gender, national origin, race, religion, sexual orientation, gender identity, or any other classification protected by European, national, or local law.

Open Transparent and Merit Based Recruitment Policy:

You can check here CIC biomaGUNE OTM-R Policy.

How To Apply:

Submit your application with a motivation letter stating why you are interested in this position, your CV, the contact details of two academics who can provide a reference using the "Apply to this Job Offer" button.

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