The scope of the seminar is to introduce the main applications of the xCELLigence RTCA DP system present at CICbioMAGUNE. This is an impedance-based and label free technology that allows in real time and physiologic conditions in a regular incubator to do assays such as cell attachment and growth, proliferation, migration and invasion, immunotoxicity, virology and drug discovery. Moreover, during the seminar it will be described the workflow, basic maintenance, and software usage.