Ordered protein-based biomaterials are highly desirable due to their applications in templating, coating, sensing, bioelectronics, catalysis, etc.  We explore strategies that rely on re-engineering interactions within biomolecules to generate ordered biomateriels with defiend structural and mechanical properties. In particicular we develop strategies to create ordered protein-based biomaterials by re-engineering protein-protein interactions inspired by rational crystal contacts engineering  and  by computational simulations.  By strategically engineering such contacts, we direct the protein to assemble into defined surpramoelcualr assemblies including biomaterials with different dimensionality.